Plasmid curing in bacteria pdf
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چکیده
Plasmids are extrachromosomal pieces of double-stranded circular DNA which have the capability to replicate independently of the.Growth dynamics of multiple component communities of bacteria. Thus curing by acridines normally involves loss of the whole plasmid.Plasmids are extrachromasomally replicating molecules of DNA present in bacteria.Plasmid curing is a process of completely removing plasmids of bacteria by.May 28, 2012. Http:bio.classes.ucsc.edubio105lEXERCISESF20TRANSFERChap126.pdf.However, many plasmids are very stable, not only because they contain multiple. And active curing strategies are needed to obtain plasmid-free bacteria.
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Enhancement of plasmid curing by 9-aminoacridine and two phenothiazines in the presence of proton pump inhibitor 1-(2-benzoxazolyl)-3,3,3-trifluoro-2-propanone.
Plasmid-containing bacteria often cause serious therapeutic failure during the treatment of infectious diseases. The selection of resistant-mutant strains and the transfer of mobile genetic determinants (such as plasmids and transposons) of resistance promote increased antibiotic resistance. In the last 30 years the antiplasmid effect of acridine dyes, ethidium bromide, sodium dodecyl sulphate ...
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